PLUMBAGIN

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1.What is the PLUMBAGIN ?

ORANGE CRYSTALLINE POWDER OR CRYSTALS

ChEBI: A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively.

Plumbagin is a natural 1,4-naphthoquinone first isolated from plants of the genus Plumbago. It has diverse effects in cells and animals. Plumbagin causes the generation of reactive oxygen species and induces apoptosis in cancer cells. It activates signaling through Nrf2 and the antioxidant response element, inducing the expression of Nrf2 target genes, including NQO1 and heme oxygenase-1 in cultured neuronal cells. Plumbagin also inhibits NADPH oxidase 4 in a time- and dose-dependent manner. It can be protective against peroxide stress or deprivation of glucose or oxygen.

2.What is the CAS number for PLUMBAGIN ?

The CAS number of PLUMBAGIN is 481-42-5.

3.What are another words for PLUMBAGIN ?

Synonyms?for?PLUMBAGIN 481-42-5:2-Methyl-5-hydroxy-1,4-naphthoquinone;2-Methyljuglone;5-Hydroxy-2-methyl-1,4-naphthoquinone;NSC 688284;

4.What is PLUMBAGIN (481-42-5) used for?

Plumbagin from Plumbago indica has been used: as a reactive oxygen species agent (ROS) to induce cytotoxicity in mouse embryonic fibroblastsas an oxidative stress inducer to generate superoxide anion in Saccharomyces cerevisiaeas a reference standard in thin layer chromatography and in spectrophotometric analysis for quantification of plumbagin in Plumbago auriculate samples

InChI:InChI=1/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

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5.Buy PLUMBAGIN with the best price .

Shijiazhuang Lianhua Chemicals Co.,Ltd. is a quality supplier of PLUMBAGIN. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on PLUMBAGIN 481-42-5.