7-Deaza-2'-C-ethynyladenosine
- CasNo:1044589-82-3
Product Description
China cas 1044589-82-3 manufacturer wholesale 7-Deaza-2'-C-ethynyladenosine at affordable price
- Molecular Formula: C13H14N4O4
- Molecular Weight: 290.279
- Boiling Point: 631.8±55.0 °C(Predicted)
- PKA: 10.48±0.70(Predicted)
- PSA: 126.65000
- Density: 1 +-.0.1 g/cm3(Predicted)
- LogP: -0.79040
1044589-82-3 Relevant articles
2'-ethynyl adenosine phosphamide derivative as well as preparation method and application thereof
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Paragraph 0078-0079; 0092-0093, (2021/11/10)
The invention relates to a compound as s...
NEW ANTIVIRAL MODIFIED NUCLEOSIDES
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Page/Page column 64, (2010/04/03)
This invention relates to novel compound...
NEW ANTIVIRAL MODIFIED NUCLEOSIDES
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Page/Page column 77, (2010/04/03)
This invention relates to novel compound...
NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS
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Page/Page column 42-43; 53, (2008/12/08)
This invention relates to novel nucleosi...
1044589-82-3 Process route
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4-amino-7-[3',5'-di-O-(4-chlorobenzyl)-2'-C-ethynyl-b-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine
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1044589-82-3
(2R,3R,4R,5R)-2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-hydroxymethyl-tetrahydro-furan-3,4-diol
| Conditions | Yield |
|---|---|
|
With
boron trichloride;
In
dichloromethane;
at -78 - -40 ℃;
for 2h;
|
84.5%
|
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1207518-58-8
(2R,3R,4R,5R)-2-(4-(isoindole-1,3-dione-2-yl)-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-hydroxymethyl-tetrahydrofuran-3,4-diol
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-
1044589-82-3
(2R,3R,4R,5R)-2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-hydroxymethyl-tetrahydro-furan-3,4-diol
| Conditions | Yield |
|---|---|
|
With
N-butylamine;
at 60 - 70 ℃;
for 2.16667h;
Inert atmosphere;
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1044589-82-3 Upstream products
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1044589-83-4
(2R,3R,4R,5R)-2-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
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1207518-58-8
(2R,3R,4R,5R)-2-(4-(isoindole-1,3-dione-2-yl)-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-hydroxymethyl-tetrahydrofuran-3,4-diol
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636581-82-3
3,5-bis-O-(2,4-dichlorobenzyl)-1-O-methyl-α-D-erythro-pentofuranos-2-ulose
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636581-81-2
3,5-bis-O-(2,4-dichlorobenzyl)-1-O-methyl-α-D-ribofuranose