NOBILETIN
- CasNo:478-01-3
Product Description
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What is the NOBILETIN ?
NOBILETIN is , while it's Molecular Formula is C21H22O8. Nobiletin is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. It is a potent antioxidant with good bioavailability. Nobiletin directly inhibits the ATP-binding cassette proteins P-glycoprotein and breast cancer resistance protein.
What is the CAS number for NOBILETIN ?
The CAS number of NOBILETIN is 478-01-3.
More information of NOBILETIN 478-01-3 are:
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Synonyms |
Flavone,3',4',5,6,7,8-hexamethoxy- (7CI,8CI);Nobiletin (6CI);2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one;3',4',5,6,7,8-Hexamethoxyflavone;5,6,7,8,3',4'-Hexamethoxyflavone;NSC 618903;NSC 76751;Nobiletin; |
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CAS?Number |
478-01-3 |
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Molecular Formula |
C21H22O8 |
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Molecular Weight |
402.401 |
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Density |
1.244 g/cm3 |
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Melting Point |
136.0 to 140.0 °C |
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Boiling Point |
587.9 °C at 760 mmHg |
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Flash Point |
256.5 °C |
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HS CODE |
29329990 |
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PSA |
85.59000 |
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LogP |
3.51160 |
What is NOBILETIN (478-01-3) used for?
Nobiletin (478-01-3) is a natural product isolated from citrus peels.? It has recently been shown to possess circadian clock amplitude-enhancing properties and was able to prevent metabolic syndrome in mice?via?a?Clock?gene-dependent mechanism.1? Nobiletin directly bound to and activated RORα/γ.? Nobiletin has previously been shown to attenuate the effects of metabolic syndrome2, have anti-neuroinflammatory effects3, possess neurotrophic activity4, and be a cancer chemopreventative agent5.
InChI:InChI=1/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H,1-6H3
Articles related to NOBILETIN:
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Article |
Source |
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Synthesis of Polymethoxyflavonoids from Hesperidin and Naringin and their Antiproliferative Activity |
Su, Liang,Jin, Zhizhong,Liu, Kexiong,Wang, Qiuan , p. 100 - 105 (2022/03/27) |
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Practical Synthesis of Polymethylated Flavones: Nobiletin and Its Desmethyl Derivatives |
Asakawa, Tomohiro,Sagara, Hiroto,Kanakogi, Masaki,Hiza, Aiki,Tsukaguchi, Yuta,Ogawa, Takahiro,Nakayama, Miho,Ouchi, Hitoshi,Inai, Makoto,Kan, Toshiyuki , p. 595 - 602 (2019/04/01) |
How to get the best price on NOBILETIN?
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