Trifluorothymine
- CasNo:54-20-6
Product Description
Manufacturer Sells Best Quality Trifluorothymine 54-20-6 with stock
- Molecular Formula: C5H3F3N2O2
- Molecular Weight: 180.086
- Appearance/Colour: white to faintly yellow crystalline powder
- Melting Point: 245-246 °C(lit.)
- Refractive Index: 1.427
- Boiling Point: 350oC
- PKA: 6.63±0.10(Predicted)
- PSA： 65.72000
- Density: 1.554 g/cm3
- LogP: 0.08200
Trifluorothymine(Cas 54-20-6) Usage
InChI:InChI=1/C5H3F3N2O2/c6-5(7,8)2-1-9-4(12)10-3(2)11/h1H,(H2,9,10,11,12)
54-20-6 Relevant articles
Polyfluorinated enamines. New methods for the synthesis of 5-trifluoromethyluracil
Popov,Pushin,Luzina
, p. 1232 - 1233 (1998)
-
Catalyst-free and visible light promoted trifluoromethylation and perfluoroalkylation of uracils and cytosines
Huang, Yang,Lei, Yun-Yun,Zhao, Liang,Gu, Jiwei,Yao, Qiuli,Wang, Ze,Li, Xiao-Fei,Zhang, Xingang,He, Chun-Yang
, p. 13662 - 13665 (2018)
Fluoroalkylated enaminones, such as trif...
Facile perfluoroalkylation of uracils and uridines at the C-5 position
Nishida, Masakazu,Fujii, Shozo,Kimoto, Hiroshi,Hayakawa, Yoshio,Sawada, Hideo,Cohen, Louis A.
, p. 43 - 52 (1993)
Perfluoroalkylation at the C-5 position ...
Use of sulfur tetrafluoride in syntheses of potential anticancer agents.
MERTES,SAHEB
, p. 508 - 509 (1963)
-
Organic semiconductor photocatalyst can bifunctionalize arenes and heteroarenes
Ghosh, Indrajit,Khamrai, Jagadish,Savateev, Aleksandr,Shlapakov, Nikita,Antonietti, Markus,K?nig, Burkhard
, p. 360 - 366 (2019/08/15)
Photoexcited electron-hole pairs on a se...
Method for preparing 5-trifluoromethyl uracil
-
Paragraph 0038-0039, (2019/06/05)
The invention belongs to the field of or...
Au@ZnO Core-Shell: Scalable Photocatalytic Trifluoromethylation Using CF3CO2Na as an Inexpensive Reagent under Visible Light Irradiation
Bazyar, Zahra,Hosseini-Sarvari, Mona
supporting information, p. 2345 - 2353 (2019/10/16)
Trifluoromethylation is of significant i...
Synthesis method of fluoropyrimidine-containing medical intermediate 2,4-dichloro-5-trifluoromethylpyrimidine
-
Page/Page column 3-6, (2018/09/28)
The invention relates to a synthesis met...
54-20-6 Process route
-
-
2926-29-6
Langlois reagent
-
-
66-22-8,144104-68-7,18324-22-6,27072-01-1,2920-92-5,51953-19-6
uracil
-
-
54-20-6
5-trifluoromethyluracil
| Conditions | Yield |
|---|---|
|
With
sodium persulfate; copper(II) sulfate;
In
water;
at 60 - 65 ℃;
for 6h;
Temperature;
Reagent/catalyst;
|
91.9%
|
|
With
mesoporous graphitic carbon nitride;
In
dimethyl sulfoxide;
at 25 ℃;
Irradiation;
|
84%
|
|
With
di-tert-butyl peroxide; sodium sulfite;
In
dichloromethane; water;
at 0 - 10 ℃;
for 8h;
|
71.1%
|
|
Langlois reagent;
In
ethyl acetate;
at 40 - 50 ℃;
for 1h;
uracil;
With
FeSO4.7H2O; silica gel;
In
water;
at 40 - 50 ℃;
With
tert.-butylhydroperoxide;
In
water;
at 40 - 70 ℃;
Time;
Reagent/catalyst;
Temperature;
|
|
|
With
tert.-butylhydroperoxide; ferrous(II) sulfate heptahydrate;
In
water;
at 45 - 70 ℃;
Reagent/catalyst;
Solvent;
Temperature;
|
73 %Chromat.
|
-
-
3932-97-6
2,4-dichloro-5-trifluoromethylpyrimidine
-
-
54-20-6
5-trifluoromethyluracil
| Conditions | Yield |
|---|---|
|
With
acetic acid;
In
water;
at 110 ℃;
for 5h;
|
90.6%
|
54-20-6 Upstream products
-
116393-64-7
N1 ,N3 -dibenzyloxymethyl-5-(trifluoromethyl)uracil
-
75-63-8
Bromotrifluoromethane
-
66-22-8
uracil
-
371-76-6
bis(trifluoromethyl)mercury
54-20-6 Downstream products
-
153364-62-6
1-(2'-O-acetyl-5'-O-benzoyl-3'-C-cyano-3'-O-mesyl-β-D-ribofuranosyl)-5-(trifluoromethyl)uracil
-
318239-85-9
(Z)-1-(2-(3,4-bis(benzyloxy)-5-oxofuran-2(5H)-ylidene)ethyl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione
-
362607-77-0
1-(3,5-di-O-benzoyl-β-L-xylo-furanosyl)-5-(trifluoromethyl)uracil
-
98406-57-6
1-benzyl-5-trifluoromethyluracil